| Alhóndiga de Granaditas A major historic building tied to Mexico's independence story, now housing a regional museum. | Museum | Centro | Map |
| Amatxi Cocina Auténtica A Presa-area restaurant listed in the official Guanajuato Capital tourism gastronomy directory. | Restaurant | Presa | Map |
| Basílica Colegiata de Nuestra Señora de Guanajuato The main basilica faces Plaza de la Paz and is one of the center's strongest architectural markers. | Church | Centro | Map |
| Bocamina San Ramón A Valenciana-area mine entrance and ex-hacienda setting that gives visitors a tangible stop for Guanajuato's silver-mining story. | Other | Valenciana | Map |
| Calle Subterránea Miguel Hidalgo The subterranean street system is one of Guanajuato's defining urban features, turning old river and tunnel infrastructure into a dramatic... | Other | Centro | Map |
| Callejón del Beso This very narrow alley is one of the city's best-known stops because of the balcony-to-balcony love legend attached to it. | Other | Centro | Map |
| Casa de Tía Aura A legend-focused house museum on Paseo de la Presa, built for visitors who like theatrical, spooky storytelling more than a conventional museum... | Museum | Presa | Map |
| Casa Mercedes A destination restaurant above the easiest center loop, often used by travelers for a more deliberate meal rather than a quick plaza stop. | Restaurant | Presa / hillside | Map |
| Casa Museo Gene Byron A Marfil house museum in the former Santa Ana hacienda, preserving the work and atmosphere of Canadian artist Gene Byron with exhibitions,... | Museum | Marfil | Map |
| Casa Valadez A long-running restaurant on Jardín de la Unión, with its own site tracing the business to 1950 and listing breakfast, lunch, and dinner service. | Restaurant | Centro | Map |
| Central de Autobuses Guanajuato The main intercity bus terminal for Guanajuato Capital, located outside the historic center on the Silao-Guanajuato road. | Transport | Los Alcaldes | Map |
| Cerro de la Bufa and Sierra de Santa Rosa A nature-and-viewpoint area for travelers who want Guanajuato beyond plazas, tunnels, and museum interiors. | Other | Sierra de Santa Rosa | Map |
| Funicular Panorámico A quick ride between the center and the Pípila viewpoint, useful for saving the steep climb and getting a moving view of the city. | Transport | Centro | Map |
| Hotel Boutique 1850 A boutique hotel directly on Jardin de la Union, useful as a location benchmark even for travelers who do not stay there. | Hotel | Centro | Map |
| Hotel Camino de Piedra A hotel and tourism-operator reference outside the tightest historic-center loop, useful for travelers comparing quieter lodging or group... | Hotel | Guanajuato | Map |
| Jardín de la Unión A shaded triangular plaza surrounded by restaurants, benches, fountains, and major landmarks. | Plaza | Centro | Map |
| La Calleja A restaurant listed in the Guanajuato Capital tourism gastronomy directory on Arboledas Street. | Restaurant | Marfil | Map |
| La Trattoria Guanajuato A Jardín de la Unión restaurant listed in the Guanajuato Capital tourism gastronomy directory. | Restaurant | Centro | Map |
| Mercado Hidalgo A central market for everyday food, casual meals, sweets, souvenirs, and local color. | Market | Centro | Map |
| Mestizo Restaurante A central restaurant option for travelers comparing a polished sit-down meal with easy access to the main historic district. | Restaurant | Centro | Map |
| Mina de Rayas A historic mine stop near Valenciana that helps explain why Guanajuato grew into one of New Spain's richest silver cities. | Other | Valenciana | Map |
| Mineral de la Luz A mining community near Guanajuato Capital that helps visitors see the city as part of a wider silver landscape, not only as a compact colonial... | Other | Mineral de la Luz | Map |
| Monumento al Pípila A hilltop monument honoring independence-era figure El Pípila, best known to visitors for its wide view over Guanajuato's colorful center. | Viewpoint | Centro | Map |
| Museo Casa de Arte Olga Costa-José Chávez Morado A former artist home in Pastita dedicated to Olga Costa and José Chávez Morado, with collections and architecture tied to an old hacienda water... | Museum | Pastita | Map |
| Museo Casa Diego Rivera The birthplace of muralist Diego Rivera preserves period rooms and presents works connected to his life and career. | Museum | Centro | Map |
| Museo Conde Rul A neoclassical mansion turned museum near Plaza de la Paz, with temporary exhibitions and historic rooms that help visitors read Guanajuato's... | Museum | Centro | Map |
| Museo de Cera de Guanajuato A small wax museum near the Alhóndiga, useful as a quick family-friendly stop when walking the lower center. | Museum | Centro | Map |
| Museo de Historia Natural Alfredo Dugès A compact natural-history museum inside the University of Guanajuato's central building, with representative specimens from a much larger... | Museum | Centro | Map |
| Museo de las Momias One of Guanajuato's most famous and unusual museums, built around naturally mummified bodies from the city cemetery. | Museum | Centro | Map |
| Museo de Mineralogía A University of Guanajuato museum at the Faculty of Mines, known for a large mineral collection that links the city’s geology with its mining... | Museum | San Javier | Map |
| Museo de Sitio Ex Convento Dieguino An archaeological-style site museum below the San Diego church, preserving remains of the former convent in the middle of the busiest visitor... | Museum | Centro | Map |
| Museo del Pueblo de Guanajuato A central museum in the former Marqués de Rayas house, with permanent and temporary rooms connected to Mexican art and Guanajuato creators. | Museum | Centro | Map |
| Museo Ex-Hacienda del Cochero A dark, theatrical museum in Valenciana with underground galleries and colonial-era punishment exhibits. | Museum | Valenciana | Map |
| Museo Ex-Hacienda San Gabriel de Barrera A former hacienda in Marfil known for its garden spaces and museum setting. | Museum | Marfil | Map |
| Museo Iconográfico del Quijote A museum devoted to artistic interpretations of Don Quixote across paintings, sculpture, tapestries, and objects. | Museum | Centro | Map |
| Museo Palacio de los Poderes A historic civic building now used as a museum space near Plaza de la Paz. | Museum | Centro | Map |
| Oajillo A compact restaurant in the Carcamanes area, useful for visitors who want a more contemporary meal without leaving the historic-center walking... | Restaurant | Centro | Map |
| Plaza de la Paz A sloped central plaza framed by the basilica, civic buildings, restaurants, and pedestrian flow. | Plaza | Centro | Map |
| Plaza de San Roque A smaller historic plaza tied to Guanajuato's performance culture and Cervantino roots. | Plaza | Centro | Map |
| Plaza San Fernando A relaxed plaza with cafes and a neighborhood feel, a little removed from the densest tourist flow. | Plaza | Centro | Map |
| Presa de la Olla A historic reservoir and promenade area south of the center. | Park | Presa | Map |
| Presa de la Olla Promenade A calmer promenade and reservoir area on the Presa side of the city, useful when the center feels too dense. | Other | Presa | Map |
| Restaurante de la Presa / Mexican Heart A Presa-side restaurant listing from Guanajuato Capital tourism, useful for visitors who want a meal away from the busiest Jardin corridor. | Restaurant | Presa | Map |
| Restaurante Posada Santa Fe The restaurant connected to Hotel Posada Santa Fe, a historic hotel facing Jardín de la Unión. | Restaurant | Centro | Map |
| Santo Café A family restaurant and cafe on Puente del Campanero. | Cafe | Centro | Map |
| Teatro Juárez Guanajuato's landmark theater anchors one side of Jardín de la Unión. | Theater | Centro | Map |
| Teatro Principal An older neoclassical theater in the historic center, often used for university and festival programming. | Theater | Centro | Map |
| Templo de San Diego The baroque church beside Jardín de la Unión and Teatro Juárez, useful as a quiet architectural pause in the busiest part of the center. | Church | Centro | Map |
| Universidad de Guanajuato Steps The university's broad steps and central facade are a classic photo and orientation point. | Other | Centro | Map |
| Valenciana and Templo de San Cayetano The Valenciana area connects Guanajuato's mining history with one of its standout baroque churches. | Historic site | Valenciana | Map |